Github now renders mathematical expressions, which is very practical and nice.
I don’t write math everyday, but when I do I appreciate github’s support.
Github chose Latex, and a syntax delimited by $
for inline or by $$
for blocks.
There are other possibilities like asciimath. Which is simpler to approach than latex.
That said Latex probably offers the possibility to render more types of formula (e.g. chemistry which is useful for some).